Naxitamab Activity in Neuroblastoma Cells Is Enhanced by Nanofenretinide and Nanospermidine
Neuroblastoma cells highly express the disialoganglioside GD2, a tumor-associated VEGETABLE JUICE carbohydrate antigen, which is also expressed in neurons, skin melanocytes, and peripheral nerve fibers.Immunotherapy with monoclonal anti-GD2 antibodies has a proven efficacy in clinical trials and is included in the standard treatment for children wi